Association between depression and subjective cognitive complaints in 47 low- and middle-income countries

Smith, Lee, Shin, Jae I., Song, Tae-Jin, Underwood, Benjamin, Jacob, Louis, Lopez-Sanchez, Guillermo, Schuch, Felipe, Oh, Hans, Veronese, Nicola, Soysal, Pinar, Butler, Laurie T., Barnett, Yvonne A. ORCID logoORCID: https://orcid.org/0000-0003-0271-2266 and Koyanagi, Ai (2022) Association between depression and subjective cognitive complaints in 47 low- and middle-income countries. Journal of Psychiatric Research, 154. pp. 28-34. ISSN 0022-3956

[img] Text
Accepted Version
Restricted to Repository staff only until 8 July 2023.
Available under the following license: Creative Commons Attribution Non-commercial No Derivatives.

Download (278kB) | Request a copy
[img] Text (Word Version)
Accepted Version
Restricted to Repository staff only until 8 July 2023.
Available under the following license: Creative Commons Attribution Non-commercial No Derivatives.

Download (134kB) | Request a copy
Official URL: https://www.sciencedirect.com/science/article/pii/...

Abstract

People with depression and subjective cognitive complaints (SCC) may be at particularly high risk for developing dementia. However, to date, studies on depression and SCC are limited mainly to single high-income countries. Thus, the aim of the present study was to investigate the association between depression and SCC in adults from low- and middle-income countries (LMICs). Cross-sectional, community-based data were analyzed from the World Health Survey. Two questions on subjective memory and learning complaints in the past 30 days were used to create a SCC scale ranging from 0 (No SCC) to 100 (worse SCC). ICD-10 Diagnostic Criteria for Research was used for the diagnosis of subsyndromal depression, brief depressive episode, and depressive episode. Multivariable linear regression was conducted to explore the associations. Data on 237,952 individuals aged ≥18 years [mean (SD) age 38.4 (16.0) years; females 50.8%] were analyzed. After adjustment for potential confounders (age, sex, education, anxiety), compared to no depressive disorder, subsyndromal depression (b-coefficient 7.91; 95%CI = 5.63–10.18), brief depressive episode (b-coefficient 10.37; 95%CI = 8.95–11.78), and depressive episode (b-coefficient 13.57; 95%CI = 12.33–14.81) were significantly associated with higher mean SCC scores. The association was similar in all age groups (i.e., 18–44, 45–64, and ≥65 years), and both males and females. All depression types assessed were associated with worse SCC among adults in 47 LMICs. Future longitudinal studies are needed to investigate whether older people with depression and SCC are at higher risk for dementia onset in LMICs.

Item Type: Journal Article
Keywords: subjective cognitive complaints, depression, LMICs, Epidemiology
Faculty: Faculty of Science & Engineering
SWORD Depositor: Symplectic User
Depositing User: Symplectic User
Date Deposited: 07 Jul 2022 10:49
Last Modified: 04 Aug 2022 11:55
URI: https://arro.anglia.ac.uk/id/eprint/707738

Actions (login required)

Edit Item Edit Item