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Exploring cognitive impairment in the early stages of an out-of-hospital cardiac arrest – a consecutive case series study

journal contribution
posted on 2023-08-30, 19:42 authored by Marco Mion, Neil Magee, Jean Davis, Kelly Farrell, Eleni Nikolopoulou, Donna Jessup, John R. Davies, Grigoris V. Karamasis, Thomas R. Keeble
Cognitive deficits are common, although often mild, in out-of-hospital cardiac arrest patients. Prevalence and severity of cognitive deficits on discharge from acute hospital, however, are not systematically assessed in clinical practice, and not frequently reported in scientific literature, potentially hindering the development of appropriate follow-up care pathways for these patients. We hereby present data from a consecutive case series of 75 out-of-hospital cardiac arrest patients discharged from our hospital over a period of 16 months; for 46 of them we were able to obtain a cognitive profile around the time of discharge from hospital, with 37 of them experiencing cognitive deficits, ranging from mild to severe. Memory, verbal fluency and cognitive flexibility were the areas more frequently impaired. The patients we were able to assess did not differ for age, cerebral performance category score and time to return of spontaneous circulation from those we were unable to assess. Cognitive deficits were not associated with duration of “no blood flow” during cardiac arrest or with age. Our results suggest that cognitive deficits in the immediate aftermath of out-of-hospital cardiac arrest are common; however, these may be missed due to lack of systematic assessment and use of poorly sensitive cognitive tests.

History

Refereed

  • Yes

Volume

0

Issue number

0

Page range

0

Publication title

Neuropsychological Rehabilitation

ISSN

1464-0694

Publisher

Taylor & Francis

File version

  • Accepted version

Language

  • eng

Legacy posted date

2022-03-09

Legacy creation date

2022-03-09

Legacy Faculty/School/Department

Faculty of Health, Education, Medicine & Social Care

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