Scotopic microperimetry: evolution, applications and future directions

Taylor, Laura J., Josan, Amandeep S., Pfau, Maximilian, Simunovic, Matthew P. and Jolly, Jasleen K. (2022) Scotopic microperimetry: evolution, applications and future directions. Clinical and Experimental Optometry. ISSN 1444-0938

Text Accepted Version Restricted to Repository staff only until 13 January 2023. Available under the following license: Creative Commons Attribution Non-commercial. Download (1MB) | Request a copy

Abstract

For many inherited and acquired retinal diseases, reduced night vision is a primary symptom. Despite this, the clinical testing options for spatially-resolved scotopic vision have until recently been limited. Scotopic microperimetry is a relatively new visual function test that combines two-colour perimetry with fundus-controlled perimetry performed in scotopic luminance conditions. The technique enables spatially-resolved mapping of central retinal sensitivity alongside the ability to distinguish between rod and cone photoreceptor sensitivities. Two companies produce commercially available scotopic microperimeters – Nidek (Nidek Technologies Srl, Padova, Italy) and CenterVue (CenterVue S.p.A., Padova, Italy). Scotopic microperimetry is a promising technology capable of detecting changes in retinal sensitivity before changes in other measures of visual function. Scotopic microperimetry is a promising functional biomarker that has potential as a useful clinical trial outcome measure. In this review, we summarise the evolution and applications of scotopic microperimetry, discuss testing options, including testing grid selection and dark-adaptation time and threshold sensitivity analyses.

Item Type:	Journal Article
Keywords:	scotopic microperimetry, microperimetry, fundus-controlled perimetry, rods, dark-adapted
Faculty:	Faculty of Health, Education, Medicine & Social Care
Depositing User:	Ian Walker
Date Deposited:	14 Jan 2022 15:25
Last Modified:	16 Mar 2022 16:21
URI:	https://arro.anglia.ac.uk/id/eprint/707255

Actions (login required)

Edit Item