Sleep problems and subjective cognitive complaints among middle-aged and older adults in 45 low- and middle-income countries

Smith, Lee and Oh, Hans and Jacob, Louis and López-Sánchez, Guillermo F. and Veronese, Nicola and Soysal, Pinar and Shin, Jae Il and Schuch, Felipe and Tully, Mark A. and Butler, Laurie T. and Barnett, Yvonne A. and Koyanagi, Ai (2022) Sleep problems and subjective cognitive complaints among middle-aged and older adults in 45 low- and middle-income countries. Aging Clinical and Experimental Research. ISSN 1720-8319

[img] Text
Accepted Version
Restricted to Repository staff only until 5 January 2023.
Available under the following license: Creative Commons Attribution Non-commercial No Derivatives.

Download (660kB) | Request a copy
[img] Text (Word version)
Accepted Version
Restricted to Repository staff only until 5 January 2023.
Available under the following license: Creative Commons Attribution Non-commercial No Derivatives.

Download (258kB) | Request a copy
Official URL: https://doi.org/10.1007/s40520-021-02052-1

Abstract

Background- Currently, a small body of evidence suggests that sleep problems are positively associated with subjective cognitive complaints (SCC). However, no studies on this topic exist from low- and middle-income countries (LMICs). Thus, we investigated the association between sleep problems and SCC in a large sample of middle-age and older adults from 45 LMICs. Methods- Cross-sectional, predominantly nationally representative, community-based data were analyzed from the World Health Survey. Sleep problems (such as difficulties falling asleep, waking up frequently during the night or waking up too early in the morning) in the last 30 days were self-reported. Two questions on subjective memory and learning complaints in the past 30 days were used to create a SCC scale ranging from 0 (No SCC) to 100 (worse SCC). Multivariable linear regression was conducted to explore the association between sleep problems (exposure) and SCC (outcome). Results- Data on 60,228 adults aged ≥ 50 years were analyzed [mean (SD) age 61.4 (9.9) years; 53.9% females]. After adjustment for potential confounders, compared to those without sleep problems, the mean SCC score for the multivariable model was 13.32 (95% CI 12.01, 14.63), 19.46 (95% CI 17.95, 20.98), 24.17 (95% CI 22.02, 26.33), and 31.39 (95% CI 28.13, 34.65) points higher for mild, moderate, severe, and extreme sleep problems, respectively. Similar results were found for analyses stratified by age and country-income level. Conclusion- Sleep problems were positively associated in a dose–response manner with SCC among middle-aged and older adults in multiple LMICs. Addressing sleep problems may aid in the prevention of SCC and ultimately dementia, pending future longitudinal research.

Item Type: Journal Article
Keywords: sleep problems, subjective cognitive complaints, older adults, low- and middle-income countries
Faculty: Faculty of Science & Engineering
SWORD Depositor: Symplectic User
Depositing User: Symplectic User
Date Deposited: 10 Dec 2021 10:21
Last Modified: 16 Mar 2022 16:21
URI: https://arro.anglia.ac.uk/id/eprint/707157

Actions (login required)

Edit Item Edit Item