Multimorbidity and anxiety symptoms among adults aged 50 years and over from six low- and middle-income countries

Smith, Lee and López-Sánchez, Guillermo F. and Shin, Jae Il and Soysal, Pinar and Veronese, Nicola and Kostev, Karel and Jacob, Louis and Oh, Hans and Schuch, Felipe B. and Butler, Laurie T. and Barnett, Yvonne A. and Law, Christopher T. and Koyanagi, Ai (2021) Multimorbidity and anxiety symptoms among adults aged 50 years and over from six low- and middle-income countries. Journal of Ageing and Longevity, 1 (1). pp. 36-47. ISSN 2673-9259

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Official URL: https://doi.org/10.3390/jal1010005

Abstract

Currently, there are limited data on the association between multimorbidity (i.e., ≥ 2 chronic conditions) and anxiety, especially among the older population in low- and middle-income countries (LMICs). Thus, the aim of the present study was to examine the association between multimorbidity and anxiety symptoms in a large sample of adults aged ≥ 50 years from six LMICs (China, India, Ghana, Mexico, Russia, South Africa). Cross-sectional, nationally representative, community-based data from the Study on Global Ageing and Adult Health (SAGE) were analysed. A total of 11 chronic physical conditions were assessed. Anxiety symptoms referred to extreme/severe problems with worry or anxiety in the past 30 days. Multivariable logistic regression and meta-analyses were conducted. Data on 34,129 adults aged ≥ 50 years were analysed (mean (SD) age 62.4 (16.0) years; 52.1% females). Compared with no chronic conditions, 2, 3, 4, and ≥ 5 chronic conditions were significantly associated with 1.47 (95% CI = 1.08–1.98), 2.46 (95% CI = 1.74–3.47), 3.04 (95% CI = 2.15–4.30), and 4.70 (95% CI = 2.99–7.38) times higher odds of anxiety symptoms, respectively. A country-wise analysis showed that multimorbidity was significantly associated with anxiety symptoms in all six countries (OR = 1.78–12.39) with the overall estimate based on a meta-analysis being OR = 2.29 (95% CI = 1.71–3.07). Multimorbidity was associated with higher odds of anxiety symptoms among older adults in LMICs. Future longitudinal studies are warranted to assess the temporal associations and mechanisms underlying this association.

Item Type: Journal Article
Keywords: multimorbidity, anxiety, LMICs, multicountry, epidemiology, older adults
Faculty: Faculty of Science & Engineering
SWORD Depositor: Symplectic User
Depositing User: Symplectic User
Date Deposited: 11 Oct 2021 12:26
Last Modified: 19 Oct 2021 11:39
URI: https://arro.anglia.ac.uk/id/eprint/707014

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