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COVID-19 and Diagnostic Testing for SARS-CoV-2 by RT-qPCR—Facts and Fallacies

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journal contribution
posted on 2023-07-26, 15:17 authored by Stephen A. Bustin, Reinhold D. Mueller, Gregory L. Shipley, Tania Nolan
Although molecular testing, and RT-qPCR in particular, has been an indispensable component in the scientific armoury targeting SARS-CoV-2, there are numerous falsehoods, misconceptions, assumptions and exaggerated expectations with regards to capability, performance and usefulness of the technology. It is essential that the true strengths and limitations, although publicised for at least twenty years, are restated in the context of the current COVID-19 epidemic. The main objective of this commentary is to address and help stop the unfounded and debilitating speculation surrounding its use.

History

Refereed

  • Yes

Volume

22

Issue number

5

Page range

2459

Publication title

International Journal of Molecular Sciences

ISSN

1422-0067

Publisher

MDPI

File version

  • Published version

Language

  • eng

Legacy posted date

2021-03-04

Legacy creation date

2021-03-04

Legacy Faculty/School/Department

Faculty of Science & Engineering

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