Optical properties of the lens: An explanation for the zones of discontinuity

Bahrami, Mehdi and Hoshino, Masato and Pierscionek, Barbara K. and Yagi, Naoto and Regini, Justyn and Uesugi, Kentaro (2014) Optical properties of the lens: An explanation for the zones of discontinuity. Experimental Eye Research, 124. pp. 93-99. ISSN 1096-0007

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Official URL: https://doi.org/10.1016/j.exer.2014.05.009

Abstract

The structural basis of zones of discontinuity in the living human eye lens has not been elucidated, and there is no conclusive explanation for what relevance they may have to the structure and function of the lens. Newly developed synchrotron radiation based X-ray Talbot interferometry has enabled the detection of subtle fluctuations in the human eye lens which, when used in mathematical modelling to simulate reflected and scattered light, can recreate the image of the lens seen in the living human eye. The results of this study show that the zones of discontinuity may be caused by subtle fluctuations in the refractive index gradient as well as from random scattering in the central regions. As the refractive index contours are created by cell layers with progressively varying protein concentrations, the zones are linked to growth and will contain information about ageing and development. The index gradient is important for image quality and fluctuations in this gradient may add to quality optimisation and serve as models for designs of new generation implant lenses.

Item Type: Journal Article
Keywords: eye lens, refractive index, zones of discontinuity, light scatter, implant design
Faculty: ARCHIVED Faculty of Health, Social Care & Education (until September 2018)
Depositing User: Lisa Blanshard
Date Deposited: 22 Feb 2021 14:44
Last Modified: 22 Feb 2021 14:44
URI: https://arro.anglia.ac.uk/id/eprint/706349

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