Tai Chi for Chronic Illness Management: Synthesizing Current Evidence from Meta-Analyses of Randomized Controlled Trials

Zou, Liye and Xiao, Tao and Cao, Chao and Smith, Lee and Imm, Kellie and Grabovac, Igor and Waldhoer, Thomas and Zhang, Yin and Yeung, Albert and Demurtas, Jacopo and Veronese, Nicola and Ekelund, Ulf and Park, Yikyung and Yang, Lin (2021) Tai Chi for Chronic Illness Management: Synthesizing Current Evidence from Meta-Analyses of Randomized Controlled Trials. American Journal of Medicine, 134 (2). pp. 194-205. ISSN 1555-7162

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Official URL: https://doi.org/10.1016/j.amjmed.2020.08.015


An umbrella review of systematic reviews and meta-analyses of randomized controlled trials (RCTs) was conducted to evaluate the existing evidence of Tai Chi as a mind-body exercise for chronic illness management. MEDLINE/PubMed and Embase databases were searched from inception until 31st March 2019 for meta-analyses of at least two RCTs that investigated health outcomes associated with Tai Chi intervention. Evidence of significant outcomes (P-value <0.05) was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. This review identified 45 meta-analyses of RCTs and calculated 142 summary estimates among adults living with 16 types of chronic illnesses. Statistically significant results (P-value <0.05) were identified for 81 of the 142 outcomes (57.0%), of which 45 estimates presenting 30 unique outcomes across 14 chronic illnesses were supported by high (n=1) or moderate (n=44) evidence. Moderate evidence suggests that Tai Chi intervention improved physical functions and disease-specific outcomes compared with non-active controls and cardiorespiratory fitness compared with active controls among adults with diverse chronic illnesses. Between-study heterogeneity and publication bias were observed in some meta-analyses.

Item Type: Journal Article
Keywords: Tai Chi, chronic illness, umbrella review, mind-body exercise, randomized controlled trial
Faculty: Faculty of Science & Engineering
SWORD Depositor: Symplectic User
Depositing User: Symplectic User
Date Deposited: 27 Aug 2020 12:58
Last Modified: 15 Sep 2021 01:02
URI: https://arro.anglia.ac.uk/id/eprint/705821

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