File(s) not publicly available
Functional vision and cognition in infants with congenital disorders of the peripheral visual system
journal contribution
posted on 2023-07-26, 14:54 authored by Naomi J. Dale, Elena Sakkalou, Michelle A. O'Reilly, Clare Springall, Michelle de Haan, Alison T. SaltAIM:
To investigate how vision relates to early development by studying vision and cognition in a national cohort of 1-year-old infants with congenital disorders of the peripheral visual system and visual impairment.
METHOD:
This was a cross-sectional observational investigation of a nationally recruited cohort of infants with 'simple' and 'complex' congenital disorders of the peripheral visual system. Entry age was 8 to 16 months. Vision level (Near Detection Scale) and non-verbal cognition (sensorimotor understanding, Reynell Zinkin Scales) were assessed. Parents completed demographic questionnaires.
RESULTS:
Of 90 infants (49 males, 41 females; mean 13mo, standard deviation [SD] 2.5mo; range 7-17mo); 25 (28%) had profound visual impairment (light perception at best) and 65 (72%) had severe visual impairment (basic 'form' vision). The Near Detection Scale correlated significantly with sensorimotor understanding developmental quotients in the 'total', 'simple', and 'complex' groups (all p<0.001). Age and vision accounted for 48% of sensorimotor understanding variance. Infants with profound visual impairment, especially in the 'complex' group with congenital disorders of the peripheral visual system with known brain involvement, showed the greatest cognitive delay.
INTERPRETATION:
Lack of vision is associated with delayed early-object manipulative abilities and concepts; 'form' vision appeared to support early developmental advance. This paper provides baseline characteristics for cross-sectional and longitudinal follow-up investigations in progress. A methodological strength of the study was the representativeness of the cohort according to national epidemiological and population census data.
History
Refereed
- Yes
Volume
59Issue number
7Page range
725-731Publication title
Developmental Medicine and Child NeurologyISSN
1469-8749External DOI
Publisher
WileyLanguage
- other
Official URL
Legacy posted date
2020-02-26Legacy Faculty/School/Department
ARCHIVED Faculty of Science & Technology (until September 2018)Note
A freely accessible copy of the author accepted manuscript is available through UCL's repository : https://discovery.ucl.ac.uk/id/eprint/10068661/Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC