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Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It?
journal contribution
posted on 2023-07-26, 14:45 authored by Pierre-Olivier Lang, Pierre Loulergue, Richard AspinallChikungunya virus (CHIKV) was until recently perceived only as a tropical disease. Since the first report of a case in Saint Martin Island in 2013, it has spread to South, Central, and North America. The first local transmission in the continental United States was reported in Florida in July 2014. CHIV infection is known to cause debilitating rheumatologic disease. Older adults are particularly susceptible to severe and chronic infection. Without an effective vaccine and antiviral therapy to prevent and control CHIKV, U.S. geriatricians could soon be confronted with major clinical, functional, and therapeutic challenges. After a general overview of CHIKV infection, this review will examine reasons why it has become such a threat to the United States and consider factors that contribute to the greater burden and effect of this disease in elderly adults. Consideration will be given to how aging and immunosenescence may contribute to CHIKV's atypical and more‐severe clinical features in older adults. This review concludes with possible therapeutic approaches that best fit the unique needs of older adults, especially with regard to multimorbidity and polypharmacy.
History
Refereed
- Yes
Volume
65Issue number
11Page range
2529-2534Publication title
Journal of the American Geriatrics SocietyISSN
1532-5415External DOI
Publisher
WileyLanguage
- other
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Legacy posted date
2019-09-10Legacy Faculty/School/Department
ARCHIVED Faculty of Health, Social Care & Education (until September 2018)Usage metrics
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