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Differences in serum magnesium levels in diabetic and non-diabetic patients following one-anastomosis gastric bypass
journal contribution
posted on 2023-09-01, 14:33 authored by Eva Winzer, Igor Grabovac, Bernhard Ludvik, Renate Kruschitz, Karin Schindler, Gerhard Prager, Carmen Klammer, Lee Smith, Friedrich Hoppichler, Rodrig Marculescu, Maria WakolbingerPatients with obesity and type 2 diabetes mellitus (T2DM) are regarded to have reduced serum magnesium (Mg) concentrations. We aimed to assess the changes in serum Mg concentrations at 12-month follow-up in patients, with and without T2DM, who underwent one anastomosis gastric bypass surgery. Overall, 50 patients (80% female, age 42.2 (12.5) years) with morbid obesity (mean baseline BMI 43.8 (4.3) kg/m2) were included in the analysis. Half of the included patients had T2DM diagnosed at baseline, and these patients showed lower serum Mg concentration (0.78 (0.07)) vs. 0.83 (0.05) mmol/L; p = 0.006), higher blood glucose levels (129.9 (41.3) vs. 87.6 (8.1) mg/dL; p < 0.001) as well as HbA1c concentrations (6.7 (1.4) vs. 5.3 (0.5)%; p < 0.001). During follow-up, BMI and glucose levels showed a decrease; however, serum Mg levels remained stable. At baseline 42% of patients were found to be Mg deficient, which was reduced to 33% at six months and to 30% at 12 months follow-up. Moreover, patients with T2DM had an odds ratio of 9.5 (95% CI = 3.0–29.7; p < 0.001) for magnesium deficiency when compared to patients without T2DM. Further research into the role of Mg and its role in T2DM and other obesity-related comorbidities are needed.
History
Refereed
- Yes
Volume
11Issue number
9Page range
1984Publication title
NutrientsISSN
2072-6643External DOI
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MDPIFile version
- Accepted version
Language
- eng
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Legacy posted date
2019-08-19Legacy creation date
2019-08-19Legacy Faculty/School/Department
Faculty of Science & EngineeringUsage metrics
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