RCP2018_KeebleFINALmanuscript.docx (59.23 kB)
Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP)
journal contribution
posted on 2023-08-30, 15:43 authored by Thomas R. Keeble, Grigoris V. Karamasis, Martin T. Rothman, Sven-Erik Ricksten, Markus Ferrari, Roger Hullin, Fredrik Scherstén, Oyvind Reitan, Sebastian T. Kirking, John G. F. Cleland, Elliot J. SmithBackground:
Worsening heart failure complicated by congestion, hypotension, and renal dysfunction is difficult to manage, increasingly common and predicts a poor outcome. Novel therapies are required to facilitate diuresis and implementation of disease-modifying interventions in preparation for hospital discharge. Accordingly, we investigated the haemodynamic and renal effects of the Reitan Catheter Pump (RCP) percutaneous support device in patients admitted with decompensated heart failure (DHF).
Methods:
This was a prospective observational study of 20 patients admitted with DHF, ejection fraction < 30%, and Cardiac index (CI) < 2.1 L/min/m2 in need of inotropic/mechanical support.
Results:
Patients underwent RCP support for a mean of 18.3 (±6.3) hours. The RCP increased CI from 1.84 L/min/m2 (±0.27), to 2.41 L/min/m2 (±0.45, p = 0.04), increased urine output (71 mL/h (±65) to 227 ml/h (±179) (p = 0.006) with a concomitant reduction in serum creatinine (188 μmol/L (±87) to 161 μmol/L (±78) (p = 0.0007). There were no clinically significant haemolysis, vascular injury, or thrombo-embolic complications.
Conclusions:
For patients admitted with DHF, the RCP improves cardiac index, diuresis and renal function without causing important complications.
History
Refereed
- Yes
Volume
275Page range
53-58Publication title
International Journal of CardiologyISSN
1874-1754External DOI
Publisher
ElsevierFile version
- Accepted version
Language
- eng
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Legacy posted date
2018-10-23Legacy creation date
2018-12-13Legacy Faculty/School/Department
Faculty of Health, Education, Medicine & Social CareUsage metrics
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