Combination of acellular dermal matrix with a de-epithelialised dermal flap during skin-reducing mastectomy and immediate breast reconstruction

Kankam, Hadyn K. N., Hourston, George J. M., Forouhi, Parto, Di Candia, Michele, Wishart, Gordon C. and Malata, Charles M. (2018) Combination of acellular dermal matrix with a de-epithelialised dermal flap during skin-reducing mastectomy and immediate breast reconstruction. Annals of The Royal College of Surgeons of England, 100 (8). e197-e202. ISSN 1478-7083

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Abstract

INTRODUCTION: Patients with large ptotic breasts undergoing immediate implant-based reconstruction often require skin-reducing mastectomy to optimise the aesthetic outcome. However, healing complications, especially at the resulting inverted T-junction, leading to wound dehiscence, infection, skin necrosis, implant exposure and failed reconstruction have been widely reported. We present an innovative approach for immediate implant-based reconstruction combining porcine- or bovine-derived acellular dermal matrices with a de-epithelialised dermal sling to protect and support the implant, while improving clinical outcomes in this challenging group of patients. MATERIALS AND METHODS: Demographic, tumour and surgical data were reviewed for patients undergoing Wise pattern (T-scar) skin-reducing mastectomies with immediate implant-based reconstruction combining porcine- or bovine-derived acellular dermal matrices with a de-epithelialised dermal sling. RESULTS: This technique was successfully employed to reconstruct five large pendulous breasts in four breast cancer patients with a median age of 50.5 years (range 34–61 years) who were not suitable for, or had declined, flap-based reconstruction. The acellular dermal matrices used were SurgiMend®, StratticeTM and Braxon® and the expandable implants were placed in the sub-pectoral (n = 3) and pre-pectoral (n = 1) planes. The technical steps and clinical outcomes are presented. One patient experienced T-junction breakdown overlying the de-epithelialised dermis without implant loss. CONCLUSION: The combination of an acellular dermal matrix and a dermal sling provides a double-layer ‘water-proofing’ and support for the implants inferiorly, avoiding T-junction breakdown complications, since any dehiscence is on to well-vascularised dermis. Furthermore, the acellular dermal matrix stabilises the implant in the large mastectomy cavity (pocket control). This approach provides a viable option which facilitates mastectomy and immediate implant reconstruction in large-breasted patients.

Item Type:	Journal Article
Keywords:	acellular dermal matrix, ADM, immediate breast reconstruction, dermal sling, de-epithelialised dermal flap, skin-reducing mastectomy, wise mammoplasty pattern
Faculty:	Faculty of Health, Education, Medicine & Social Care
Depositing User:	Ian Walker
Date Deposited:	08 Aug 2018 07:56
Last Modified:	10 Jun 2022 12:29
URI:	https://arro.anglia.ac.uk/id/eprint/703470

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