Veronese, Nicola and Stubbs, Brendon and Noale, Marianna and Solmi, Marco and Rizzoli, Renè and Vaona, Alberto and Demurtas, Jacopo and Crepaldi, Gaetano and Maggi, Stefania (2018) Adherence to a Mediterranean diet is associated with lower incidence of frailty: A longitudinal cohort study. Clinical Nutrition, 37 (5). pp. 1492-1497. ISSN 1532-1983
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Abstract
Background & aims: There is a paucity of data investigating the relationship between the Mediterranean diet and frailty, with no data among North American people. We aimed to investigate if adherence to a Mediterranean diet is associated with a lower incidence of frailty in a large cohort of North American people. Methods: This study included subjects at higher risk or having knee osteoarthritis. Adherence to the Mediterranean diet was evaluated using a validated Mediterranean diet score (aMED) as proposed by Panagiotakos and classified into five categories. Frailty was defined using the Study of Osteoporotic Fracture (SOF) index as the presence of ≥2 out of: (i) weight loss ≥5% between baseline and the subsequent follow-up visit; (ii) inability to do five chair stands; (iii) low energy level. Results: During the 8 years follow-up, of the 4421 participants initially included (mean age: 61.2 years, % of females = 58.0), the incidence of frailty was approximately half in those with a higher adherence to the Mediterranean diet (8 for 1000 person years) vs. those with a lower adherence (15 for 1000 persons-years). After adjusting for 10 potential confounders (age, sex, race, body mass index, education, smoking habits, yearly income, physical activity level, Charlson co-morbidity index and daily energy intake), participants with the highest aMED scores were found to have a significant reduction in incident frailty (hazard ratio = 0.71; 95% CIs: 0.50–0.99, p = 0.047) with respect to those in a lower category. Regarding individual components of the Mediterranean diet, low consumption of poultry was found to be associated with higher risk of frailty. Conclusions: A higher adherence to a Mediterranean diet was associated with a lower incidence of frailty over an 8-year follow-up period, even after adjusting for potential confounders.
Item Type: | Journal Article |
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Keywords: | Frailty, Mediterranean diet, Osteoarthritis initiative, Older people |
Faculty: | ARCHIVED Faculty of Health, Social Care & Education (until September 2018) |
Depositing User: | Brendon Stubbs |
Date Deposited: | 02 Oct 2017 15:35 |
Last Modified: | 09 Sep 2021 18:56 |
URI: | https://arro.anglia.ac.uk/id/eprint/702231 |
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