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Pharmacological cognitive enhancement: treatment of neuropsychiatric disorders and lifestyle use by healthy people

journal contribution
posted on 2023-07-26, 14:07 authored by Barbara J. Sahakian, Sharon Morein-Zamir
Neuropsychiatric disorders typically manifest as problems with attentional biases, aberrant learning, dysfunctional reward systems, and an absence of top-down cognitive control by the prefrontal cortex. In view of the cost of common mental health disorders, in terms of distress to the individual and family in addition to the financial cost to society and governments, new developments for treatments that address cognitive dysfunction should be a priority so that all members of society can flourish. Cognitive enhancing drugs, such as cholinesterase inhibitors and methylphenidate, are used as treatments for the cognitive symptoms of Alzheimer's disease and attention deficit hyperactivity disorder. However, these drugs and others, including modafinil, are being increasingly used by healthy people for enhancement purposes. Importantly for ethical and safety reasons, the drivers for this increasing lifestyle use of so-called smart drugs by healthy people should be considered and discussions must occur about how to ensure present and future pharmacological cognitive enhancers are used for the benefit of society.

History

Refereed

  • Yes

Volume

2

Issue number

4

Page range

357-362

Publication title

The Lancet Psychiatry

ISSN

2215-0374

Publisher

Elsevier

Language

  • other

Legacy posted date

2017-07-04

Legacy creation date

2017-06-27

Legacy Faculty/School/Department

ARCHIVED Faculty of Science & Technology (until September 2018)

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