High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia

Alsultan, Abdulrahman A., Evans, Benjamin A., Elsayed, Elsayed A., Al-Thawadi, Sahar I., Al-Taher, Abdulla Y., Amyes, Sebastian G. B., Al-Dughaym, Abdullah M. and Hamouda, Ahmed (2013) High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia. Journal of Medical Microbiology, 62 (6). pp. 885-888. ISSN 1473-5644

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Abstract

Carbapenem-resistant Acinetobacter baumannii is becoming increasingly prevalent in patients with diabetes mellitus in the Middle East. We examined the relationship of these bacteria and their resistance mechanisms to the diabetic disease status of patients in Saudi Arabia. Susceptibilities of 271 isolates to carbapenems, tigecycline and colistin were determined, followed by detection of carbapenemase genes. A blaVIM gene was detected in ~95 % of isolates; blaOXA-23 and blaOXA-40 genes were also prevalent. Diabetic patients were significantly more likely to carry carbapenem-resistant isolates. Carbapenem-resistant A. baumannii is a serious problem in diabetic patients, and molecular detection of resistance mechanisms in these isolates is required.

Item Type:	Journal Article
Faculty:	ARCHIVED Faculty of Science & Technology (until September 2018)
Depositing User:	Repository Admin
Date Deposited:	20 May 2014 13:37
Last Modified:	09 Sep 2021 19:02
URI:	https://arro.anglia.ac.uk/id/eprint/317227

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