Simultaneous detection of controlled substances in waste water

Mwenesongole, Ellen M., Gautam, Lata, Hall, Sarah, Waterhouse, John S. and Cole, Michael D. (2013) Simultaneous detection of controlled substances in waste water. Analytical Methods, 13 (5). pp. 3248-3254. ISSN 1759-9679

Accepted Version
Available under the following license: Creative Commons Attribution Non-commercial No Derivatives.

Download (114kB) | Preview
Official URL:


This study presents a method of simultaneous detection of both traditional and newly emerged drugs of abuse in wastewater. The method is based on solid phase extraction and gas chromatography-mass spectrometry analysis. This analytical method separates 25 drugs from different classes including amphetamines, cathinones, tropane alkaloids, piperazines plus ketamine, amitriptyline, diazepam and morphine. In addition, newer compounds (methcathinone, mephedrone, butylone), and isomers (1-(2-methoxyphenyl) piperazine, 1-(4-methoxyphenyl) piperazine; 1-(2-flurophenyl) piperazine, 1-(4-flurophenyl) piperazine; 1-(3-trifluoromethylphenyl) piperazine, 1-(4-trifluoromethylphenyl) piperazine) have been separated, with greater sensitivity (×100 order of magnitude). This work reports the detection of butylone, mephedrone, 1-(4-methoxyphenyl) piperazine, 1-(2-flurophenyl) piperazine and 1-methyl-4-benzylpiperazine for the first time in waste water. This suggests that with changes in drug use patterns, constant monitoring of waste water entering treatment plants should be carried out and treatment processes need to be put in place for their removal.

Item Type: Journal Article
Faculty: ARCHIVED Faculty of Science & Technology (until September 2018)
Depositing User: Repository Admin
Date Deposited: 05 Nov 2013 12:08
Last Modified: 09 Sep 2021 19:02

Actions (login required)

Edit Item Edit Item