Simultaneous detection of controlled substances in waste water.pdf (111.64 kB)
Simultaneous detection of controlled substances in waste water
journal contribution
posted on 2023-08-30, 13:54 authored by Ellen M. Mwenesongole, Lata Gautam, Sarah Hall, John S. Waterhouse, Michael D. ColeThis study presents a method of simultaneous detection of both traditional and newly emerged drugs of abuse in wastewater. The method is based on solid phase extraction and gas chromatography-mass spectrometry analysis. This analytical method separates 25 drugs from different classes including amphetamines, cathinones, tropane alkaloids, piperazines plus ketamine, amitriptyline, diazepam and morphine. In addition, newer compounds (methcathinone, mephedrone, butylone), and isomers (1-(2-methoxyphenyl) piperazine, 1-(4-methoxyphenyl) piperazine; 1-(2-flurophenyl) piperazine, 1-(4-flurophenyl) piperazine; 1-(3-trifluoromethylphenyl) piperazine, 1-(4-trifluoromethylphenyl) piperazine) have been separated, with greater sensitivity (×100 order of magnitude). This work reports the detection of butylone, mephedrone, 1-(4-methoxyphenyl) piperazine, 1-(2-flurophenyl) piperazine and 1-methyl-4-benzylpiperazine for the first time in waste water. This suggests that with changes in drug use patterns, constant monitoring of waste water entering treatment plants should be carried out and treatment processes need to be put in place for their removal.
History
Refereed
- Yes
Volume
13Issue number
5Page range
3248-3254Publication title
Analytical MethodsISSN
1759-9679External DOI
Publisher
Royal Society of ChemistryFile version
- Accepted version
Language
- eng
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Legacy posted date
2013-11-05Legacy creation date
2019-05-20Legacy Faculty/School/Department
ARCHIVED Faculty of Science & Technology (until September 2018)Usage metrics
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