Qualitative detection of the NSAIDs diclofenac and ibuprofen in the hair of Eurasian otters (Lutra lutra) occupying UK waterways with GC–MS

Richards, Ngaio L. and Cook, Gemma and Simpson, Vic and Hall, Sarah and Harrison, Nancy M. and Scott, Karen S. (2011) Qualitative detection of the NSAIDs diclofenac and ibuprofen in the hair of Eurasian otters (Lutra lutra) occupying UK waterways with GC–MS. European Journal of Wildlife Research, 57. pp. 1107-1114. ISSN 1439-0574

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1007/s10344-011-0513-2


The pervasiveness of pharmaceuticals such as nonsteroidal anti-inflammatory drugs (NSAIDs) in the aquatic ecosystem through the discharge of wastewater, and their potential to biomagnify within this ecosystem, is now recognised. Residues of diclofenac and ibuprofen are currently being detected in surface waters and aquatic organisms throughout the UK and Europe. However, the levels of these residues in fish and other aquatic organisms, particularly lower trophic level prey species, have not yet been determined. While exposure to diclofenac is known to adversely affect fish, the degree to which other aquatic organisms are exposed and impacted through continuous ingestion of contaminated prey and interaction with the aquatic habitat remains unknown. The extent and effects of exposure to ibuprofen also remain largely unknown. As an exploratory subset of a broader study to investigate the detectability of diclofenac in alternative biological matrices, we analysed hair samples from Eurasian otters (Lutra lutra, n = 28) for residues of the two NSAIDs using GC–MS. The otters were collected from six counties in England as part of an ongoing otter health monitoring project at the Wildlife Veterinary Investigation Centre in Chacewater, UK. Diclofenac was qualitatively detected in five hair wash and 15 extract samples, and ibuprofen was determined to be present in at least two of the hair extract samples. Here, we provide preliminary evidence that otters are exposed to both NSAIDs and argue for further studies to identify residue loads in the otters and their prey to fully assess the pervasiveness of these compounds and potential risks of ongoing exposure to them.

Item Type: Journal Article
Keywords: Non-invasive monitoring, Aquatic ecosystem contamination, Pharmaceutical contamination, Hair analysis, NSAID
Faculty: ARCHIVED Faculty of Science & Technology (until September 2018)
Depositing User: Repository Admin
Date Deposited: 17 Sep 2013 14:07
Last Modified: 09 Sep 2021 16:17
URI: https://arro.anglia.ac.uk/id/eprint/301732

Actions (login required)

Edit Item Edit Item