Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP)

Keeble, Thomas R. and Karamasis, Grigoris V. and Rothman, Martin T. and Ricksten, Sven-Erik and Ferrari, Markus and Hullin, Roger and Scherstén, Fredrik and Reitan, Oyvind and Kirking, Sebastian T. and Cleland, John G. F. and Smith, Elliot J. (2019) Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP). International Journal of Cardiology, 275. pp. 53-58. ISSN 1874-1754

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Official URL: https://doi.org/10.1016/j.ijcard.2018.09.085

Abstract

Background: Worsening heart failure complicated by congestion, hypotension, and renal dysfunction is difficult to manage, increasingly common and predicts a poor outcome. Novel therapies are required to facilitate diuresis and implementation of disease-modifying interventions in preparation for hospital discharge. Accordingly, we investigated the haemodynamic and renal effects of the Reitan Catheter Pump (RCP) percutaneous support device in patients admitted with decompensated heart failure (DHF). Methods: This was a prospective observational study of 20 patients admitted with DHF, ejection fraction < 30%, and Cardiac index (CI) < 2.1 L/min/m2 in need of inotropic/mechanical support. Results: Patients underwent RCP support for a mean of 18.3 (±6.3) hours. The RCP increased CI from 1.84 L/min/m2 (±0.27), to 2.41 L/min/m2 (±0.45, p = 0.04), increased urine output (71 mL/h (±65) to 227 ml/h (±179) (p = 0.006) with a concomitant reduction in serum creatinine (188 μmol/L (±87) to 161 μmol/L (±78) (p = 0.0007). There were no clinically significant haemolysis, vascular injury, or thrombo-embolic complications. Conclusions: For patients admitted with DHF, the RCP improves cardiac index, diuresis and renal function without causing important complications.

Item Type: Journal Article
Keywords: decompensated heart failure, congestion, cardiac support, renal dysfunction
Faculty: Faculty of Medical Science
Depositing User: Ian Walker
Date Deposited: 23 Oct 2018 07:49
Last Modified: 13 Dec 2018 14:26
URI: http://arro.anglia.ac.uk/id/eprint/703724

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