Relationship between sedentary behavior and depression: a mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries

Stubbs, Brendon and Vancampfort, Davy and Firth, Joseph and Schuch, Felipe and Hallgren, Mats and Smith, Lee and Gardner, Benjamin and Kahl, Kai and Veronese, Nicola and Solmi, Marco and Carvalho, Andre F. and Koyanagi, Ai (2018) Relationship between sedentary behavior and depression: a mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries. Journal of Affective Disorders, 229. pp. 231-238. ISSN 1573-2517

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Official URL: http://dx.doi.org/10.1016/j.jad.2017.12.104

Abstract

Background: Sedentary behavior (SB) is associated with diabetes, cardiovascular disease and low mood. There is a paucity of multi-national research investigating SB and depression, particularly among low- and middle-income countries. This study investigated the association between SB and depression, and factors which influence this. Methods: Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. Depression was based on the Composite International Diagnostic Interview. The association between depression and SB (self-report) was estimated by multivariable linear and logistic regression analyses. Mediation analysis was used to identify influential factors. Results: A total of 42,469 individuals (50.1% female, mean 43.8 years) were included. People with depression spent 25.6 (95%CI8.5-42.7) more daily minutes in SB than non-depressed participants. This discrepancy was most notable in adults aged ≥65 y (35.6 minutes in those with depression). Overall, adjusting for socio-demographics and country, depression was associated with a 1.94 (95%CI1.31-2.85) times higher odds for high SB (i.e., ≥8 h/day). The largest proportion of the SB-depression relationship was explained by mobility limitations (49.9%), followed by impairments in sleep/energy (43.4%), pain/discomfort (31.1%), anxiety (30.0%), disability (25.6%), cognition (16.1%), and problems with vision (11.0%). Other health behaviors (physical activity, alcohol consumption, smoking), body mass index, and social cohesion did not influence the SB-depression relationship. Conclusion: People with depression are at increased risk of engaging in high levels of SB. This first multi-national study offers potentially valuable insight for a number of hypotheses which may influence this relationship, although testing with longitudinal studies is needed.

Item Type: Journal Article
Keywords: Sedentary Behaviour, Sitting, Physical activity, Depression, Low- and middle-income countries
Faculty: Faculty of Science & Technology
Depositing User: Lee Smith
Date Deposited: 04 Jan 2018 15:19
Last Modified: 03 Jan 2019 02:02
URI: http://arro.anglia.ac.uk/id/eprint/702586

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