Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study

Walker, Robert W. and Cheah, Kevin and Ingle, Paul and Mootanah, Rajshree (2013) Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study. Journal of Computer Science & Systems Biology, 6. pp. 305-310. ISSN 0974-7230

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Official URL: https://doi.org/10.4172/0974-7230.1000126

Abstract

Bovine patella cartilage shows signs of damage and cell death when subjected to a compressive cyclic load of 6 MPa, which results in a shear stress of 5.6 MPa. The aim of this research was to investigate the effect of activities of daily living (descending stairs, bicycling and deep flexion) on the contact stresses in the patellofemoral compartment following an articular chondrocyte implantation (ACI). A finite element (FE) model of the patellar femoral joint was created and dynamic non-linear analyses were carried out for this purpose. A shear stress of 5.6 MPa was used as the threshold that cartilage can tolerate without resulting in damage. The FE model was verified numerically. Our results show that, for a 70 kg individual at 50% recovery, (i) contact stress in the patella is 11% higher than that in the femur; (ii) shear stress in the host cartilage reaches 4.75 MPa at 50° of flexion; (iii) shear stress in the patella host cartilage is twice that in a healthy cartilage during deep flexion approaching 70°; (iv) maximum shear stress value was 2.75 MPa during cycling at 60% load; (v) stress shielding still occurs through the host cartilage even when the implanted cartilage reaches 97.5% the Young’s modulus of a healthy cartilage. Based on these results, (i) using an exercise bicycle is recommended for rehabilitation; (ii) deep knee flexion should be avoided; (iii) obese people with a BMI of over 42 kg/m2 should not undertake vigorous weight-bearing exercises involving deep knee flexion.

Item Type: Journal Article
Keywords: Autologous chondrocyte implantation, Patellofemoral joint, Finite element method, Knee cartilage, Shear stress, Contact stress
Faculty: Faculty of Science & Technology
Depositing User: Lisa Blanshard
Date Deposited: 30 Nov 2017 11:10
Last Modified: 30 Nov 2017 11:10
URI: http://arro.anglia.ac.uk/id/eprint/702486

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