Free operant observing in humans: a translational approach to compulsive certainty seeking

Morein-Zamir, Sharon and Shahper, Sonia and Fineberg, Naomi A. and Eisele, Verena and Eagle, Dawn M. and Urcelay, Gonzalo and Robbins, Trevor W. (2018) Free operant observing in humans: a translational approach to compulsive certainty seeking. The Quarterly Journal of Experimental Psychology, 71 (10). pp. 2052-2069. ISSN 1747-0226

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Official URL: http://dx.doi.org/10.1177/1747021817737727

Abstract

Excessive checking is reported in non-clinical populations and is a pervasive symptom in obsessive compulsive disorder (OCD). We implemented a free-operant task in humans, previously used in rats, wherein participants can “check” to reduce uncertainty. Participants can press an observing key to ascertain which of two main keys will, if pressed, currently lead to rewards. Over a series of experiments, we found that punishment robustly increased observing in non-clinical participants and that observing persisted long after punishment was removed. Moreover, participants appeared insensitive to the initial costs of checking, and a threefold increase in the effort required to observe served to deter participants only to a limited degree. We also assessed observing in OCD patients with no known comorbidities. The patients observed more than control participants and were abnormally insensitive to the introduction of punishment. These findings support the translational value of the task, with similar behaviours in humans and rodents. This paradigm may serve as a unifying platform, promoting interaction between different approaches to analyse adaptive and maladaptive certainty seeking behaviours. Specifically, we demonstrate how seemingly disparate theoretical and empirical approaches can be reconciled synergistically to promote a combined behavioural and cognitive account of certainty seeking.

Item Type: Journal Article
Keywords: Psychology, Observing, Checking, Intolerance of Uncertainty, Obsessive Compulsive Disorder
Faculty: Faculty of Science & Technology
Depositing User: Sharon Morein
Date Deposited: 28 Sep 2017 13:13
Last Modified: 01 Jan 2019 02:02
URI: http://arro.anglia.ac.uk/id/eprint/702157

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