Mosaic tetracycline resistance genes encoding ribosomal protection proteins

Warburton, Philip J. and Amodeo, Nina and Roberts, Adam P. (2016) Mosaic tetracycline resistance genes encoding ribosomal protection proteins. Journal of Antimicrobial Chemotherapy. dkw304. ISSN 0305-7453

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Official URL: http://doi.org/10.1093/jac/dkw304

Abstract

First reported in 2003, mosaic tetr acycline resistance genes are a subgroup of the genes encoding ribosomal protection proteins (RPPs). They are formed when two or more RPP-encoding genes recombine resulting in a functional chimera. To date, the majority of mosaic genes are derived from sections of three RPP genes, tet (O), tet (W) and tet (32), with others comprising tet (M) and tet (S). In this first review of mosaic genes, we report on their structure, diversity and prevalence, and suggest that these genes may be responsible for an under- reported contribution to tetracycline resistance in bacteria

Item Type: Journal Article
Faculty: Faculty of Science & Technology
Depositing User: Ian Walker
Date Deposited: 27 Oct 2016 13:33
Last Modified: 10 Apr 2017 13:10
URI: http://arro.anglia.ac.uk/id/eprint/701017

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