New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity

Fineberg, Naomi A. and Chamberlain, Samuel R. and Goudriaan, Anna E. and Stein, Dan J. and Vanderschuren, Louk J. M. J. and Gillan, Claire M. and Shekar, Sameer and Gorwood, Philip A. P. M. and Voon, Valerie and Morein-Zamir, Sharon and Denys, Damiaan and Sahakian, Barbara J. and Moeller, F. Gerard and Robbins, Trevor W. and Potenza, Marc N. (2014) New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity. CNS Spectrums, 19 (1). pp. 69-89. ISSN 2165-6509

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Official URL: https://doi.org/10.1017/S1092852913000801

Abstract

Impulsivity and compulsivity represent useful conceptualizations that involve dissociable cognitive functions, which are mediated by neuroanatomically and neurochemically distinct components of cortico-subcortical circuitry. The constructs were historically viewed as diametrically opposed, with impulsivity being associated with risk-seeking and compulsivity with harm-avoidance. However, they are increasingly recognized to be linked by shared neuropsychological mechanisms involving dysfunctional inhibition of thoughts and behaviors. In this article, we selectively review new developments in the investigation of the neurocognition of impulsivity and compulsivity in humans, in order to advance our understanding of the pathophysiology of impulsive, compulsive, and addictive disorders and indicate new directions for research.

Item Type: Journal Article
Faculty: Faculty of Science & Technology
Depositing User: Repository Admin
Date Deposited: 04 Mar 2016 15:35
Last Modified: 16 May 2019 11:26
URI: http://arro.anglia.ac.uk/id/eprint/600636

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