Visual impairment and blindness due to macular diseases globally: a systematic review and meta-analysis.

Jonas, Jost B. and Bourne, Rupert R. A. and White, Richard A. and Flaxman, Seth R. and Keeffe, Jill and Leasher, Janet and Naidoo, Kovin and Pesudovs, Konrad and Price, Holly C. and Wong, Tien Y. and Resnikoff, Serge and Taylor, Hugh R. (2014) Visual impairment and blindness due to macular diseases globally: a systematic review and meta-analysis. American Journal of Ophthalmology, 158 (4). pp. 808-815. ISSN 1879-1891

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Official URL: https://doi.org/10.1016/j.ajo.2014.06.012

Abstract

Purpose: To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy. Design: Meta-analysis. Methods: Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60) due to macular diseases, with diabetic maculopathy excluded. Results: In 2010, of 32.4 million blind people and 191 million vision-impaired people, 2.1 million (95% uncertainty interval [UI]: 1.9, 2.7) people were blind, and 6.0 million (95% UI: 5.2, 8.1) million were visually impaired due to macular diseases. In 2010, macular diseases caused 6.6% (95% UI: 6.0, 7.9) of all blindness and 3.1% (95% UI: 2.7, 4.0) of all vision impairment, worldwide. These figures were lower in regions with young populations than in high-income regions. Between 1990 and 2010, the number of people who were blind or visually impaired due to macular diseases increased by 36%, or 0.6 million people (95% UI: 0.5, 0.8) and by 81%, or 2.7 million (95% UI: 2.6, 3.9) people, respectively, whereas the global population increased by 30%. Age-standardized global prevalence of macula-related blindness and vision impairment in adults 50 years of age and older decreased from 0.2% (95% UI: 0.2, 0.2) in 1990 to 0.1% (95% UI: 0.1, 0.2) in 2010 and remained unchanged from 0.4% (95% UI: 0.3, 0.5) to 0.4% (95% UI: 0.4, 0.6), respectively. Conclusions: In 2010, 2.1 million people were blind and 6.0 million people were visually impaired due to macular diseases, except those caused by diabetic maculopathy. Of every 15 blind people, 1 was blind due to macular disease, and of every 32 visually impaired people, 1 was visually impaired due to macular disease.

Item Type: Journal Article
Faculty: ARCHIVED Faculty of Science & Technology (until September 2018)
Depositing User: Repository Admin
Date Deposited: 12 Aug 2015 09:57
Last Modified: 14 Nov 2019 16:02
URI: http://arro.anglia.ac.uk/id/eprint/566191

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