Ni Cr Milk.docx (790.23 kB)
The Toxicological Analysis of Ni and Cr in Prescription Food for Special Medical Purposes and Modified Milk Products for Babies in Infancy Available in Pharmacies in Poland
journal contribution
posted on 2023-08-30, 16:06 authored by Kamil Jurowski, Mirosław Krośniak, Maria Fołta, Barbara Tatar, Michael D. Cole, Wojciech PiekoszewskiPrescription food for special medical purposes (FSMPs) and modified milk products (MMPs) for babies in the infancy period available in pharmacies are increasingly frequently used for newborns and infants—especially in cases where allergies and food-borne diseases are diagnosed. However, there is a lack of scientific study around the safety assessment of the elemental impurities in these products. Importantly, the allergen Ni and the problematic metal Cr are little considered. Hence, the aim of this article was the toxicological analysis of Ni and Cr impurities in prescription FSMPs (n = 6) and MMPs (n = 6) for newborns and infants available in Polish pharmacies. For the best safety assessment, we include three approaches including (1) the levels of Ni and Cr in powdered products, (2) assessment of the daily dose depending on age and body weight of newborns and infants, and (3) the weekly intake of Ni and Cr in samples in comparison to provisional tolerable weekly intake (PTWI). Our results show that, on the basis of our data, the products from pharmacies in Poland investigated in this study do not represent a real health hazard to newborns and infants, although there may be a requirement for the monitoring of levels of Ni. Our results are pioneer and provide valuable data for other scientists and manufacturers.
History
Refereed
- Yes
Volume
192Issue number
2Page range
129-135Publication title
Biological Trace Element ResearchISSN
1559-0720External DOI
Publisher
SpringerFile version
- Accepted version
Language
- eng
Official URL
Legacy posted date
2019-03-07Legacy creation date
2019-03-07Legacy Faculty/School/Department
Faculty of Science & EngineeringUsage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC