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Neural reactivation in parietal cortex enhances memory for episodically linked information

journal contribution
posted on 2023-09-01, 14:25 authored by Tanya R. Jonker, Halle Dimsdale-Zucker, Maureen Ritchey, Alex Clarke, Charan Ranganath
Remembering is a complex process that involves recalling specific details, such as who you were with when you celebrated your last birthday, as well as contextual information, such as the place where you celebrated. It is well established that the act of remembering enhances long-term retention of the retrieved information, but the neural and cognitive mechanisms that drive memory enhancement are not yet understood. One possibility is that the process of remembering results in reactivation of the broader episodic context. Consistent with this idea, in two experiments, we found that multiple retrieval attempts enhanced long-term retention of both the retrieved object and the nontarget object that shared scene context, compared with a restudy control. Using representational similarity analysis of fMRI data in experiment 2, we found that retrieval resulted in greater neural reactivation of both the target objects and contextually linked objects compared with restudy. Furthermore, this reactivation occurred in a network of medial and lateral parietal lobe regions that have been linked to episodic recollection. The results demonstrate that retrieving a memory can enhance retention of information that is linked in the broader event context and the hippocampus and a posterior medial network of parietal cortical areas (also known as the Default Network) play complementary roles in supporting the reactivation of episodically linked information during retrieval.

History

Refereed

  • Yes

Volume

115

Issue number

43

Page range

11084-11089

Publication title

Proceedings of the National Academy of Sciences

ISSN

1091-6490

Publisher

National Academy of Sciences

File version

  • Other

Language

  • eng

Legacy posted date

2019-01-17

Legacy Faculty/School/Department

Faculty of Science & Engineering

Note

A copy of this paper is available at https://www.repository.cam.ac.uk/handle/1810/285143

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