High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia.pdf (160.31 kB)
High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia
journal contribution
posted on 2023-08-30, 14:00 authored by Abdulrahman A. Alsultan, Benjamin A. Evans, Elsayed A. Elsayed, Sahar I. Al-Thawadi, Abdulla Y. Al-Taher, Sebastian G. B. Amyes, Abdullah M. Al-Dughaym, Ahmed HamoudaCarbapenem-resistant Acinetobacter baumannii is becoming increasingly prevalent in patients with diabetes mellitus in the Middle East. We examined the relationship of these bacteria and their resistance mechanisms to the diabetic disease status of patients in Saudi Arabia. Susceptibilities of 271 isolates to carbapenems, tigecycline and colistin were determined, followed by detection of carbapenemase genes. A blaVIM gene was detected in ~95 % of isolates; blaOXA-23 and blaOXA-40 genes were also prevalent. Diabetic patients were significantly more likely to carry carbapenem-resistant isolates. Carbapenem-resistant A. baumannii is a serious problem in diabetic patients, and molecular detection of resistance mechanisms in these isolates is required.
History
Refereed
- Yes
Volume
62Issue number
6Page range
885-888Publication title
Journal of Medical MicrobiologyISSN
1473-5644External DOI
Publisher
Microbiology SocietyFile version
- Accepted version
Language
- eng
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2014-05-20Legacy creation date
2021-04-22Legacy Faculty/School/Department
ARCHIVED Faculty of Science & Technology (until September 2018)Usage metrics
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