High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia

Alsultan, Abdulrahman A. and Evans, Benjamin A. and Elsayed, Elsayed A. and Al-Thawadi, Sahar I. and Al-Taher, Abdulla Y. and Amyes, Sebastian G. B. and Al-Dughaym, Abdullah M. and Hamouda, Ahmed (2013) High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia. Journal of Medical Microbiology. ISSN 0022-2615

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Abstract

Carbapenem-resistant Acinetobacter baumannii is becoming increasingly prevalent in patients with diabetes mellitus in the Middle East. We examined the relationship of these bacteria and their resistance mechanisms to the diabetic disease status of patients in Saudi Arabia. Susceptibilities of 271 isolates to carbapenems, tigecycline and colistin were determined, followed by detection of carbapenemase genes. A blaVIM gene was detected in ~95 % of isolates; blaOXA-23 and blaOXA-40 genes were also prevalent. Diabetic patients were significantly more likely to carry carbapenem-resistant isolates. Carbapenem-resistant A. baumannii is a serious problem in diabetic patients, and molecular detection of resistance mechanisms in these isolates is required.

Item Type: Journal Article
Additional Information: Citation: Al-Sultan, A. A., Evans, B. A., Elsayed, E. A., Al-Thawadi, S. I., Al-Taher, A. Y., Amyes, S. G. B., Al-Dughaym A. M. & Hamouda, A., 2013. High frequency of carbapenem-resistant Acinetobacter baumannii in patients with Diabetes Mellitus in Saudi Arabia. Journal of Medical Microbiology, 62(6) pp. 885-888; published online ahead of print March 21, 2013..
Faculty: Faculty of Science & Technology
Depositing User: Mr I Walker
Date Deposited: 20 May 2014 13:37
Last Modified: 29 Jun 2017 11:51
URI: http://arro.anglia.ac.uk/id/eprint/317227

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